Appropriate Use Of Statistical Tools

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...to determine the efficacy and safety of continuous treatment with infliximab, a monochlonal antibody, as an intervention with patients suffering from psoriasis. In this double-blind study, patients either received infusions of infliximab or a placebo (Reich, et al, 2005). At weeks 10 and 24 of the trial, statistical tests, specifically Pearson tests, were employed n order to compare the proportions of patients responding to treatment. Furthermore, continuous response parameters were analyzed utilizing a two-sample t test on van der Waerden normal scores, with normal scores derived from all ranks (Reich, et al, 2005). The following examination of these statistical tools looks at whether or not these particular methods were the most appropriate means for evaluating this study data. (As this writer/tutor did not possess any personal knowledge on which to formulate an opinion on this question, additional sources had to be consulted.)
First of all, Pearson's chi-square test is a statistical procedure that is used to find the difference between observed and theoretical frequency (Pearson's, 2005)....

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